Malaria The region has made serious strides towards a malaria-free future. Between 2000 and 2015 malaria deaths plunged from 7,842 per year to 1,098. Overall malaria cases decreased by 75 percent in 14 countries. The Global Fund provides 86 percent of the external financial support necessary for malaria control in the region. Despite this progress, approximately 1.5 billion people remain at risk of malaria in the Asia-Pacific. New challenges are emerging such as resistance to artemisinin - the world’s most effective malaria medicine. The Global Fund’s Regional Artemisinin Initiative brings together the health ministries of Laos, Thailand, Cambodia, Myanmar and Vietnam to expand the roll-out of insecticide-treated mosquito nets and case management in areas where there is drug resistance. Surveillance systems are expanding and efforts are underway to halt the marketing of substandard antimalarial drugs.