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The vision of the Global Fund is to achieve a world free of the burden of HIV, TB and malaria. The strategy is to invest for impact.

The impact of investments in health can be measured in many ways, including how many lives are saved, and the rate of decline in HIV, TB and malaria, and other methods. In a broad sense, the real impact of investments in health is the vitality and economic strength of communities and countries where the burden of disease is retreating. 

In 2000, AIDS, tuberculosis and malaria appeared to be unstoppable. The world fought back. As a partnership of governments, the private sector, civil society and people affected by the diseases, the Global Fund pooled the world’s resources to invest strategically in programs to end AIDS, TB and malaria as epidemics. It is working.

The Global Fund partnership supports programs that have saved more than 22 million lives as of 2016.

We can’t stop now. We need to accelerate our efforts to build on this amazing progress and prevent a resurgence of the diseases. Our partnership has set performance targets for the Global Fund Strategy 2017-2022. Programs supported by the Global Fund will save 14 million lives in the three-year period beginning in 2017, bringing the total lives saved by the Global Fund partnership to 36 million by the end of 2019. Those programs will also avert up to 194 million new infections or cases of HIV, TB and malaria.

Decline in HIV burden

In the past 15 years, the Global Fund and our partners have achieved what was once considered impossible. The number of HIV-related deaths has been cut by nearly half, from 1.9 million people at the peak of the crisis to 1 million in 2016.

The rapid increase in access to ARV therapy in countries supported by the Global Fund – from 3 percent coverage in 2005 to 21 percent in 2010 and 52 percent in 2016 – has been a tremendous contributing factor. Through Global Fund-supported programs, more than 11 million people are receiving lifesaving ARV therapy – more than half the total number of people on treatment worldwide.

The number of HIV infections is falling. Between 2000 and 2016, the number of new HIV infections declined by 40 percent in countries supported by the Global Fund. Global Fund-supported programs have provided 4.2 million HIV-positive mothers with treatment to prevent transmission of HIV to their babies.

“We have bent the trend lines of tuberculosis and malaria – two of humanity’s ancient foes – and we have prevented AIDS from reaching its catastrophic potential.”
Marijke Wijnroks, Chief of Staff, Global Fund

Decline in TB burden

Overall, the story of progress against TB is commendable. Global TB treatment programs averted 49 million deaths between 2000 and 2015 (including 10 million HIV-positive people).

The number of deaths from TB in 2015 would have been more than three times higher in absence of interventions. In countries supported by the Global Fund, the mortality rate from TB declined 35 percent and actual deaths declined 21 percent between 2000 and 2015 (excluding HIV-positive people). Additionally, the number of TB cases in countries where the Global Fund invests went down 5 percent between 2005 and 2015.

Decline in malaria burden

The fight against malaria is the biggest success story of the 21st century. The number of deaths caused by malaria globally declined 50 percent between 2000 and 2015 – that translates to an estimated 6.8 million deaths averted. The number of malaria cases has declined rapidly, dropping by more than 18 percent in that same period, resulting in a total of 1.3 billion malaria cases averted globally between 2001 and 2015.

The simplest and most effective malaria preventive tool is a long-lasting insecticidal net that a family can hang over their sleeping area. More than 795 million mosquito nets have been distributed through Global Fund-supported programs.

Cases of malaria treated through Global Fund-supported programs rose 15 percent in the past year alone, to hit a cumulative total of 668 million by end 2016.

Results Report 2017

Full Report
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We capture our impact and results in our annual report, which is available for download.

Our Results Report 2017 delivers a summary of the impact and results achieved through the end of 2016 by programs supported by the Global Fund, showing cumulative progress since 2002. It is a collective effort, combining the strong contributions made by governments, civil society, the private sector and people affected by HIV, TB and malaria.

AIDS, TB & Malaria: End It. For Good.

The Global Fund marks the tremendous progress made collectively by partners in the fight against AIDS, TB and malaria, and calls for a renewed commitment to accelerating the end of these epidemics. 22 million lives have already been saved by Global Fund supported programs, and defeating these diseases could be among our generation’s greatest achievements. We can’t stop now.

Published 13 September 2017