Seventh Replenishment

South Africa

Seventh Replenishment Preparatory Meeting Co-host

South Africa has been part of the Global Fund partnership since 2002. During this time, significant progress has been made in the fight against HIV, tuberculosis (TB) and malaria in the country.

Key achievements in the country include:

  • Between 2010 and 2020, the number of AIDS-related deaths decreased by 50%, from 164,000 annually to 83,000.
  • The number of people living with HIV receiving antiretroviral (ARV) treatment tripled from 23% in 2010 to 72% in 2020.
  • Coverage of medication that prevents mother-to-child transmission of HIV increased from 71% in 2010 to 95% in 2020.
  • The success rate for treating multi-drug resistant TB increased from 40% in 2010 to 60% in 2017.
  • The number of HIV patients with TB who have access to ARVs increased from 54% in 2010 to 85% in 2019.

Private sector partnership:

In South Africa, Zenysis Technologies, a data integration and analytics company, has supported three civil society organizations that deliver a range of HIV prevention programs to key and vulnerable populations including sex workers and adolescent girls and young women. The organizations used Zenysis’ platform to integrate fragmented program and finance data to build a complete overview of their HIV prevention programs. With the consolidated data, they are better able to understand program performance and client retention and expenditure, which helps enhance operational efficiency. By integrating different data streams, the organizations have also streamlined their reporting to donors, including to the Global Fund, and strengthened their operational planning to better deliver services (Learn more).


The Global Fund/Karin Schermbrucker

Health Hero

Meet Nombasa Krune-Dumile, a drug-resistant TB counselor from Cape Town.


Visit South Africa country profile.