# Global Fund Report Shows Countries Fought to Protect Essential Health Services Despite Challenging Year

[هذا خالل واجهتها التي التحديات رغم األساسية الصحية الخدمات لحماية جاهدة الدول سعي عن يكشف العالمي الصندوق تقرير العا](https://www.theglobalfund.org/media/cjij55cw/media_2026-09-16-report-shows-countries-fought-protect-essential-health-services_newsrelease_ar.pdf)

[Un
            informe del Fondo Mundial muestra la lucha de los países
            para proteger los servicios de salud esenciales en un año
            complejo](https://www.theglobalfund.org/media/vg3hcn4w/media_2026-09-16-report-shows-countries-fought-protect-essential-health-services_newsrelease_es.pdf)

[Der
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            Jahres haben Länder sich für die Sicherung lebenswichtiger
            Gesundheitsleistungen engagiert](https://www.theglobalfund.org/media/jb3f2uuw/media_2026-09-16-report-shows-countries-fought-protect-essential-health-services_newsrelease_de.pdf)

[Il
            rapporto del Global Fund dimostra la resilienza dei Paesi nella protezione dei servizi sanitari essenziali
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            un anno difficile](https://www.theglobalfund.org/media/aishsvzk/media_2026-09-16-report-shows-countries-fought-protect-essential-health-services_newsrelease_it.pdf)

[グローバルファンドの成果報告書、厳しい一年の中でも、各国が
            不可欠な保健医療サービスを守るために尽力したことを示す](https://www.theglobalfund.org/media/3rrdgr4k/media_2026-09-16-report-shows-countries-fought-protect-essential-health-services_newsrelease_jp.pdf)

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            서비스를 지켜내기 위한 각국의 노력 조명](https://www.theglobalfund.org/media/5o1laovo/media_2026-09-16-report-shows-countries-fought-protect-essential-health-services_newsrelease_ko.pdf)

**GENEVA** – Countries and partners showed remarkable resilience in the fight against HIV, TB and malaria in 2025, as they worked together to protect hard-won gains during one of the toughest periods in global health, according to the Global Fund’s 2026 Results Report released today.

Across more than 100 countries where the Global Fund invests, governments, communities, civil society and bilateral and multilateral partners adapted to mounting pressures – from sharp cuts in international funding to conflict, displacement and growing humanitarian need – to sustain essential services and protect more than two decades of progress against the three diseases. The Global Fund partnership worked alongside countries to address critical gaps, sustain essential programs and accelerate access to innovation.

Despite this resilience, 2025 also served as a stark reminder of how fragile those gains can be. Funding disruptions contributed to significant setbacks across the three diseases: HIV prevention services were scaled back or suspended in many countries, TB programs faced disruptions to case finding, diagnosis and treatment, and malaria responses saw stock-outs of essential medicines and delays to critical prevention campaigns.

## Leadership under pressure

“This year’s results demonstrate what is possible when countries lead and partners adapt around their priorities,” **said Peter Sands, Executive Director of the Global Fund**. “Faced with extraordinary pressure, countries, communities and partners worked together to protect essential services and safeguard decades of progress against HIV, TB and malaria. As countries take greater ownership of their health responses, we have an opportunity to accelerate change, embrace innovation and deliver greater impact from every dollar.”

Despite these pressures, countries continued delivering significant results in 2025, with the support of the Global Fund partnership:

- **26.9 million** people were on antiretroviral therapy for HIV, compared to 25.6 million in 2024;
- **7.4 million** people were treated for TB, sustaining the progress of 2024; and
- **196 million** insecticide-treated mosquito nets were distributed, compared to 162 million in 2024.

Since 2002, the Global Fund partnership has helped save **72 million lives**.

## Progress against HIV, TB and malaria

### HIV and AIDS

Countries maintained HIV treatment and continuity of care despite significant pressures on health systems and funding. In 2025, 87% of people living with HIV in Global Fund-supported countries knew their status, 80% were receiving antiretroviral therapy and 74% had achieved viral suppression. HIV prevention services, however, were hit hard by reductions in domestic and international funding. In 2025, 1.1 million people received pre-exposure prophylaxis (PrEP) in countries where the Global Fund invests, down from 1.4 million in 2024. These setbacks underscore the urgent need to restore prevention efforts and protect hard-won gains against HIV.

### Tuberculosis

Countries worked to protect access to essential TB diagnosis and treatment amid severe funding pressures. In 2025, 7.4 million people were treated for TB in Global Fund-supported countries, including 115,000 people with drug-resistant TB. In 2024, an estimated 10.7 million people fell ill with TB globally and more than 1.2 million died from the disease. Significant gaps in diagnosis and treatment persist, reinforcing the need to find, diagnose and treat more people earlier.

### Malaria

Countries worked to sustain lifesaving malaria services despite funding disruptions, conflict, climate change and growing insecticide resistance. While essential medicines and time-sensitive interventions were disrupted in many countries, the Global Fund partnership continued to prioritize high-impact prevention. In 2025, 196 million insecticide-treated mosquito nets were distributed. Yet malaria claimed an estimated 610,000 lives globally in 2024, highlighting the need to protect access to essential services and accelerate progress against the disease.

## Delivering where the needs are greatest

A disproportionate share of the burden of HIV, TB and malaria is concentrated in some of the world’s most challenging settings. Fragile and conflict-affected settings account for around 63% of global malaria cases, while countries experiencing acute or protracted crises bear around one-quarter of global TB cases.

The Global Fund directs significant resources to these settings, adapting its approach to sustain lifesaving services in the face of conflict, displacement, disease outbreaks and other emergencies. Across the 2024-2026 period, the Global Fund is investing US$5.3 billion – 38% of total investments – in challenging operating environments. Emergency Funding provides rapid, flexible financing when crises threaten essential HIV, TB and malaria services and existing grants cannot be reprogrammed quickly enough. Between 2014 and 2025, the Global Fund awarded US$156.9 million through the Emergency Fund to 39 countries.

## Innovation is accelerating progress

As countries seek greater impact with constrained resources, innovation is becoming an increasingly powerful tool for accelerating progress. The report highlights the first deliveries of the breakthrough HIV prevention tool lenacapavir to Global Fund-supported early-adopter countries at the end of 2025, followed by accelerated scale-up in 2026, the rollout of AI-enabled digital X-rays to more than 20 countries in the fight against TB, and the continued scale-up of dual active ingredient insecticide-treated mosquito nets for malaria, which have the potential to reduce malaria cases by up to 45% in areas of insecticide resistance compared with standard nets.

Partnerships across governments, the private sector, manufacturers and technical organizations are also helping new health technologies reach the countries that need them faster. Through market shaping, pooled procurement and coordinated product introduction, the Global Fund partnership is helping game-changing tools reach low- and middle-income countries almost simultaneously with high-income countries – dramatically shortening a historic lag that could previously stretch to five years or more.

## Investing in stronger health systems and global health security

With the United Nations High-Level Meeting on Pandemic Prevention, Preparedness and Response taking place next week, this year’s findings reinforce how Global Fund investments strengthen health systems and global health security. Between 2024 and 2026, the Global Fund is investing approximately US$5.9 billion in health and community systems – a 43% increase over the previous grant cycle and the largest health systems investment in its history. Investments in laboratories, disease surveillance, medical oxygen, supply chains, community health workers and primary healthcare help countries detect outbreaks earlier, respond faster and build more resilient health systems. This investment has been bolstered by the Global Fund’s COVID-19 Response Mechanism, which mobilized over US$5 billion to support both the immediate COVID-19 response and the longer-term strengthening of critical health system infrastructure and capacities, including laboratory systems, disease surveillance, the health workforce and oxygen infrastructure – strengthening preparedness for future health threats.

The ongoing 2026 Ebola outbreak in the Democratic Republic of the Congo demonstrates these investments in action. Building on systems and capacities strengthened through existing Global Fund investments, the partnership has rapidly mobilized resources to reinforce epidemiological surveillance, laboratory diagnostics, contact tracing, case management and infection prevention and control, while also supporting malaria prevention in Ebola-affected areas. The Global Fund rapidly mobilized US$6.4 million from existing grants and approved an additional US$4.6 million in Emergency Funding for the response.

## Country leadership will shape the next chapter

This year’s Results Report demonstrates how country leadership, innovation and partnership helped protect decades of progress against HIV, TB and malaria – while reinforcing the need for the Global Fund partnership to continue evolving in support of more sustainable and self-reliant country responses.

Looking ahead, the Global Fund is already putting that evolution into practice. Strategic shifts approved in late 2025 are sharpening the prioritization of resources, strengthening support for countries on the path to self-reliance and creating clearer and more predictable transition pathways. They place greater emphasis on domestic co-financing and resource mobilization, deeper integration into national health systems and the long-term sustainability of community systems.

The disruption of 2025 has also created an opportunity to accelerate wider change – with greater efficiency and effectiveness, stronger country ownership and a relentless focus on achieving the greatest impact from every dollar. As countries increase their investments and advance toward greater self-reliance, sustained international investment will remain critical. With countries and communities in the lead, and donors and partners helping sustain momentum, the Global Fund partnership can protect hard-won gains and accelerate progress towards ending AIDS, TB and malaria as public health threats.