Malaria is both preventable and treatable, and great progress has been made in the last decade alone. New methods of testing, the widespread distribution of insecticide-treated nets and the introduction of artemisinin-based combination therapies (ACTs) have led to a 29 percent drop in malaria deaths between 2000 and 2015. But these gains remain fragile. If efforts are neglected, malaria could resurge within just one infectious season. Global funding for malaria has grown to US$2.5 billion per year, but this is less than half the amount required to maintain the gains against this disease. There are other challenges in the response to malaria. Growing resistance to artemisinin and its partner drugs, as well as resistance to the insecticide used on nets, is threatening the response in much of Southeast Asia. The use of nets for other than their intended purpose also poses a threat to prevention and control efforts. Weak health management information systems make monitoring outbreaks and the impact of prevention efforts much more difficult. Reducing the impact of malaria involved a multipronged plan that includes education, prevention, diagnosis, treatment and monitoring.