Pandemic or Not, Medical Oxygen Remains Essential

12 January 2024 by Peter Sands, Executive Director, The Global Fund

Among the most shocking images from the COVID-19 pandemic were of people gasping for air, unable to breathe, their blood oxygen so severely depleted that some died in ambulances lined up outside hospitals. In wealthier countries, there was a panicked rush to expand ventilator capacity to deal with the surge of people experiencing acute respiratory distress. In countries like India and Kenya, there was an even more desperate scramble to find oxygen cylinders for loved ones. In low- and middle-income countries, nine out of ten hospitals lacked the equipment to provide oxygen therapy.

Seeing people dying for lack of oxygen, the Global Fund to Fight AIDS, Tuberculosis, and Malaria, Unitaid, USAID, and other global agencies took action. Under the umbrella of the Access to COVID-19 Tools Accelerator, we established the Oxygen Emergency Taskforce to coordinate the emergency response, broaden access, and secure supplies. Since then, the taskforce has overseen an investment exceeding US$1 billion for oxygen-related needs, primarily via the Global Fund COVID-19 Response Mechanism (C19RM). These funds have gone toward procuring oxygen cylinders and bulk storage tanks, installing oxygen production machines (known as pressure swing adsorption plants), and offering specialized training for health workers.

Tragically, this response came too late for too many people, because the peak of the pandemic coincided with a worldwide shortage of oxygen cylinders. Furnishing a hospital with a sustainable oxygen supply takes many months, given the need to install sophisticated equipment and pipework; and training health workers to provide oxygen safely cannot be done overnight.

Following the acute phase of the pandemic, the Oxygen Emergency Taskforce’s focus shifted toward ensuring greater access to medical oxygen on a sustainable basis, so that what happened with COVID-19 is never repeated. Moreover, there is a compelling case for expanding access to medical oxygen even without the threat of a pandemic. Lack of oxygen in low- and middle-income countries leads to 800,000 preventable deaths every year. Newborn babies die of respiratory distress syndrome. Mothers die when complications in childbirth result in hypoxemia. Acute trauma victims – from violence or traffic accidents, for example – also die from lack of oxygen. Surgical procedures for a wide range of conditions, including cancer, cannot be carried out without medical oxygen.

It would be difficult to identify a better example of an investment that simultaneously reinforces pandemic preparedness and saves lives now. Research by the Every Breath Counts Coalition shows that hospitals that offer pediatric care with a fully functioning supply of oxygen can reduce deaths due to child pneumonia by almost half, and all children’s deaths by one-quarter.

Judy Mwaura (left), a paediatrician at Muranga Level 5 Hospital in Murang'a County, Kenya, treats a child in the hospital's children's ward. The Global Fund/Brian Otieno

To maintain the pace of progress in expanding access to medical oxygen, the Global Fund and Unitaid, alongside other partners, have transformed the Oxygen Emergency Taskforce into a Global Oxygen Alliance, known as GO2AL. Its objectives are to provide financial support for oxygen production and supply, comprehensive technical and training assistance, and advocacy for equitable access.

National governments are also taking the lead. For example, this past April, Kenyan President William Ruto and county governors set aside US$41 million for a program to distribute medical oxygen cylinders and bulk storage tanks to the country’s health-care centers. With the support of the Global Fund and other partners, Kenya also is building a nationwide network of oxygen-production plants, bulk-storage tanks, and cylinder distribution channels to ensure that hospitals and primary care facilities have sufficient supplies.

Far too many people died from lack of oxygen during the COVID-19 pandemic, and far too many are dying unnecessarily today from other conditions because medical oxygen is not routinely available. That is why we have embarked on the most ambitious effort yet to increase access to medical oxygen in low- and middle-income countries.

To date, and thanks to the generosity of donors led by the United States and Germany, the Global Fund has invested US$617 million to support 98 countries and six regional projects in their efforts to increase access to oxygen. Doing so will save millions of lives and significantly improve low- and middle-income countries’ ability to respond to future disease threats.

Sadly, nothing will bring back the people who died gasping for air. But owing to our unified response to COVID-19, millions of others can be spared a similar fate.

This op-ed was first published in Project Syndicate.