Eighth Replenishment Stop At Nothing.

Published: 04 November 2025

The Global Fund’s Eighth Replenishment Summit took place on Friday, 21 November 2025, in Johannesburg, South Africa. This Summit marks a pivotal moment to accelerate the fight to end AIDS, TB and malaria, strengthen resilient and sustainable health systems, and build a healthier, safer future for all.

As co-hosts, South Africa and the UK are championing solidarity, sustainability, innovation, equity and reform — principles at the heart of the Global Fund’s partnership model. 

The event convened heads of state and government, civil society, communities, multilateral and bilateral partners, and the private sector to secure the investments needed to expand lifesaving health programs. 

Together, we have the opportunity to save up to 23 million lives and move closer to a world free from the deadliest infectious diseases. We must stop at nothing to end AIDS, TB and malaria.

Global Fund Partners Demonstrate Unity and Resolve to Sustain Progress and Strengthen Global Health Security

Learn more


Global Fund Private Sector Partners to Drive Innovation, Equity, Access and Impact in Global Health

Learn more


Pledges at Global Fund Eighth Replenishment Conference

download in English


Pledges at Global Fund Eighth Replenishment Conference - Private Sector and Non-Government Donors

download in English

Why support the Global Fund? Because it works. Because together, we’ve made unstoppable progress against the deadliest infectious diseases. Because we strengthen health systems and save lives on a massive scale. Because where you live shouldn’t determine whether you live. 70 million lives saved. Millions more to go. Together, we must Stop at Nothing to end AIDS, TB and malaria.

Latest News

Our Impact

Results Report 2025

The 2025 Results Report captures a pivotal moment in the Global Fund partnership’s fight against HIV, tuberculosis (TB) and malaria. After decades of progress, global health is in crisis. Declining international funding is jeopardizing the fight against AIDS, TB and malaria – and with it, global health security. But our partnership is addressing these challenges head-on and seeking effective solutions. In 2024, we continued to advance the fight against the three diseases decisively forward.

Learn More

Patterns of Past, Present, Promise

Patterns of Past, Present, Promise: A Ritual of Resilience

Sibulele Sibaca Nomnganga’s story is one of loss, love and lasting hope. Orphaned by AIDS, she became a caregiver as a child – and a fighter for change as an adult. Inspired by her resilience, Sibu’s story was brought to life as a pattern by artist Mbhali Manzini. Sibu calls on the world for renewed commitment to finally defeat HIV. We are so close, we cannot stop now.

Learn More

Patterns of Past, Present, Promise: A Life Reborn

I was pregnant with my first child when I was diagnosed with drug-resistant tuberculosis (TB). I’d already suffered years of misdiagnosis. In an instant, all the joy I felt as an expectant mother turned to fear and anxiety.

Learn More

Patterns of Past, Present, Promise

I was 18 when I was diagnosed with HIV. The months leading up to my diagnosis were filled with fear and confusion. I wanted to donate blood, to do something good – but what followed was a series of healthcare missteps and poor communication. Eventually I received the news I’d been so afraid of – I was HIV positive.

Learn More

Patterns of Past, Present, Promise: After the Rain

When I was four years old, I lost my father to malaria. Since then, I’ve lost my baby niece, I almost lost my mother, and I came close to death myself. All because of malaria.

Learn More

Share