The Global Fund’s Eighth Replenishment Summit took place on Friday, 21 November 2025, in Johannesburg, South Africa. This Summit marks a pivotal moment to accelerate the fight to end AIDS, TB and malaria, strengthen resilient and sustainable health systems, and build a healthier, safer future for all.
As co-hosts, South Africa and the UK are championing solidarity, sustainability, innovation, equity and reform — principles at the heart of the Global Fund’s partnership model.
The event convened heads of state and government, civil society, communities, multilateral and bilateral partners, and the private sector to secure the investments needed to expand lifesaving health programs.
Together, we have the opportunity to save up to 23 million lives and move closer to a world free from the deadliest infectious diseases. We must stop at nothing to end AIDS, TB and malaria.


