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About the Global Fund

Twenty years ago, AIDS, tuberculosis (TB) and malaria seemed unbeatable. In 2002, in an act of extraordinary global solidarity and leadership, the world came together to create the Global Fund to fight what were then the deadliest infectious diseases confronting humanity.

Over the more than 20 years that followed, the Global Fund partnership has invested more than US$60 billion, saving 59 million lives and reducing the combined death rate from the three diseases by more than half in the countries where we invest.

Our Mission

The Global Fund is a worldwide partnership to defeat HIV, TB and malaria and ensure a healthier, safer, more equitable future for all. We raise and invest more than US$5 billion a year to fight the deadliest infectious diseases, challenge the injustice that fuels them, and strengthen health systems and pandemic preparedness in more than 100 of the hardest hit countries. In 2022, the Global Fund disbursed a record US$5.2 billion to fight HIV, TB and malaria, support COVID-19 Response Mechanism (C19RM) activities and strengthen the systems for health that underpin any pandemic response. We unite world leaders, communities, civil society, health workers and the private sector to find solutions that have the most impact, and we take them to scale worldwide.

To achieve the greatest impact against the deadliest infectious diseases, we challenge power dynamics to ensure affected communities have an equal voice in the fight and an equal chance at a healthy future. By working together, we are getting close to achieving the goals the world once deemed impossible – ending HIV, TB and malaria as public health threats.

How We Work

The Global Fund raises funds on a three-year cycle, bringing longer term predictability in the fight against AIDS, TB and malaria and in reinforcing resilient and sustainable systems for health. Governments, the private sector and foundations pledge funds to support our mission. As a global health partnership, we also work closely with partners in the public and private sectors to harness insights and innovation.

Countries where the Global Fund invests take the lead in determining where and how to best fight the three diseases, and present funding applications for review by different Global Fund structures. Country ownership allows them to tailor their own response, considering their political, cultural and epidemiological context.

The Global Fund takes on rigorous reviews of funding applications. Once the applications have been approved, Principal Recipients and Global Fund Country Teams work together to prepare a grant that countries can then implement. Together with implementing countries, the Global Fund monitors and assesses activities through different review structures and mechanisms to ensure funding achieves its intended purpose. The results of these assessments are reported back to donors.

Our Results and Impact

The coverage of treatment and prevention interventions for HIV, TB and malaria in countries where the Global Fund invests has grown markedly since 2002. Scientific advances, innovative ideas and private sector know-how are unlocking improvements in disease prevention, treatment and care.

Health programs supported by the Global Fund partnership have saved 59 million lives since we were created in 2002, reducing the combined death rate from HIV, TB and malaria by more than half. The lives saved include parents who care for their children, employers and workers that build thriving economies, neighbors and friends that contribute to their communities. They are children who have survived malaria, or who have been protected from HIV and are now young adults. They are community leaders who strive every day to make the lives of people in their communities better, healthier, and longer. Every life saved and every infection averted has a multiplier effect.

Read the Latest Results Report

Published: 12 September 2022