Change chart data

The Results Report highlights the significant strides the Global Fund partnership has made in the fight against HIV, tuberculosis (TB) and malaria in 2023.

The results we have achieved in the last year build on an extraordinary record of progress: Since 2002, our partnership has cut the combined death rate from AIDS, TB and malaria by 61%. In 2023, we reached a new milestone on our journey to end HIV, TB and malaria as public health threats: We put more people on antiretroviral treatment for HIV than ever before, we found and put on treatment more people with TB than ever before, and we distributed a record number of mosquito nets to prevent malaria.

In 2023 the Global Fund made an unprecedented level of investments to build strong health and community systems, mitigating the impact of today’s global crises on the health programs that we fund. We played a critical role in supporting countries and communities to advance human rights and gender equality by breaking down barriers to health and ensuring access to lifesaving care to those who need it most.

Key Results and Lives Saved

Since our inception in 2002, health programs supported by the Global Fund partnership have saved 65 million lives.

Key Results:

Programmatic results achieved during 2023 by countries and regions where the Global Fund invests. Global Fund Regional Groupings.

The coverage of key treatment and prevention interventions for HIV, TB and malaria in countries where the Global Fund invests has increased significantly since our founding. In 2023, 78% of people living with HIV were on antiretroviral therapy, up from 22% in 2010. TB treatment coverage reached 70% in 2022, up from 45% in 2010. The percentage of the population with access to a long-lasting insecticide-treated net reached 57% in 2022, up from 30% in 2010.

By putting people and communities at the center of all our work, we continued to deliver on our promise to save lives from HIV, TB and malaria and help countries build stronger and more inclusive health and community systems. Our investments have played a pivotal role in helping to increase life expectancy in low- and middle-income countries. Millions of people in sub-Saharan Africa are living longer, largely because of the gains made in the fight against HIV, TB and malaria.

We measure our progress against the targets in the global plans for HIV, TB and malaria and in the Sustainable Development Goal (SDG) 3 of health and well-being for all. Our achievements are the result of efforts by a wide array of actors comprising the Global Fund partnership, including governments, multilateral agencies, bilateral partners, the private sector, civil society groups, and people and communities affected by the three diseases.

Coverage of treatment and prevention interventions

HIV - % of people living with HIV on antiretroviral therapy
Tuberculosis - % of TB treatment coverage
Malaria - % of population with access to a long-lasting insecticide-treated net
Malaria coverage is calculated based on 38 African countries where the Global Fund invests, for which data is available from WHO/Malaria Atlas Project estimates. HIV and TB estimates are based on all countries where the Global Fund invests. Based on published data from WHO (2023 release for TB and malaria) and UNAIDS (2024 release). Global Fund Regional Groupings
Eight-year-old Rehana Bosan tested positive for HIV at 4 years old. Rehana was diagnosed during Ratodero’s 2019 HIV outbreak, likely caused by unsafe medical practices and contaminated medical supplies.
Our investments in the fight against HIV, TB and malaria have been among the most powerful tools in reducing global health inequities. We must finish the fight against the three diseases to eliminate these health inequities once and for all.
2024 Results Report

Lucy Mukasia, a clinician at Kibera Health Centre in Nairobi, Kenya, sorts antiretroviral medicines.

HIV: State of the Fight

Key HIV results in 2023 in countries where the Global Fund invests:

Programmatic results achieved during 2023 by countries and regions where the Global Fund invests. Global Fund Regional Groupings.

The world continues to make remarkable gains against HIV – the end of AIDS as a public health threat is within reach.

In 2023, the Global Fund continued to invest strongly in HIV treatment, including interventions focused on enrolling and maintaining more people on lifesaving care. Twenty-five million people were on lifesaving antiretroviral therapy in countries where the Global Fund invests in 2023, up from 17.5 million in 2017. In 2023, the Global Fund, together with partners and generic pharmaceutical manufacturers, secured a price reduction of 25% for the preferred first-line HIV treatment, enabling governments to invest in other critical areas of their HIV programs, save more lives and reduce new infections.

Our investments in HIV prevention focused on increasing access to the interventions that have the greatest impact on reducing new HIV infections. In the countries where we invest, 17.9 million people were reached with HIV prevention services, including 8 million people from key populations and 8.5 million young people. We continued to support countries to address societal and structural factors that fuel the HIV epidemic, promoting and protecting human rights and addressing other inequalities that predispose people to the virus.

People living with HIV who know their status

People living with HIV receiving ARVs

People living with HIV with suppressed viral load

Prevention of mother-to-child transmission coverage

All data is based on estimates from UNAIDS 2024 release. Global Fund disbursements are available on the Global Fund Data Explorer. The denominator for the three 95s is people living with HIV. The data for disease burden estimate and service coverage reflects that available from UNAIDS at the time of publication. Global Fund Regional Groupings.
Sex workers test for HIV and sexually transmitted infections at a mobile clinic operated out of a van in Phnom Penh, Cambodia. The mobile clinic offers rapid diagnostic tests, HIV self-tests, condoms and educational materials on preventing HIV and sexually transmitted infections.

Global Fund investments not only drive progress in tackling HIV, but also contribute to building strong, equitable and resilient health and community systems. In 2023, investments in training health care workers, improving laboratory infrastructure and integrating HIV services into broader health systems accelerated country-led responses to HIV while supporting progress in the fight against other diseases and strengthening pandemic preparedness.

But our fight isn’t over yet. In 2023, 39.9 million people were living with HIV globally, 1.3 million people were newly infected with the virus, and 630,000 people died of AIDS-related causes. We must significantly scale up efforts and resources if the world is to meet the SDG 3 target of ending AIDS as a public health threat by 2030.

HIV Infections Among Adolescent Girls and Young Women

Gender inequality has long been recognized as a powerful driver of the HIV epidemic. Adolescent girls and young women (aged 15 to 24) are still disproportionately affected. But Global Fund investments in 13 priority countries have led to a 69% reduction in the HIV incidence rate amongst adolescent girls and young women in these countries since 2010. In 2023, 2.6 million adolescent girls and young women were reached with HIV prevention programs in these priority countries. The Global Fund has also invested in HIV treatment and prevention programs focusing on boys and men, including voluntary medical male circumcision as well as efforts to address harmful cultural and social norms that influence HIV transmission.

Reduction in HIV incidence rate among women aged 15-24

</svg >% change 2010-2022 in 13 priority countries
</svg >Bubble size represents new HIV infections, 2022
HIV burden estimates from UNAIDS, 2024 release.

Trends in HIV Burden

In countries where the Global Fund invests, AIDS-related deaths have been reduced by 73% since the Global Fund was founded in 2002 and new infections have been reduced by 61%. In the absence of HIV prevention and HIV treatment measures and antiretroviral medicines, deaths would have increased by 115% and new HIV infections by 119% in the same period. The world has made remarkable progress in the response to HIV – we’ll work together to finish the fight by 2030.

With prevention and ARVs (actual)
If there had been no prevention or ARVs

Trends in AIDS-related deaths

Trends in new HIV infections

HIV burden estimates from UNAIDS, 2024 release. Estimation of “no prevention or ARVs” trends from Goals, AEM and AIM models where available. For some countries estimates of burden are not available from UNAIDS. Global Fund portfolio indicates countries that have recently received Global Fund HIV and AIDS funding and have reported programmatic results over the past two cycles. Global Fund Regional Groupings.
Ion Popescu used drugs for 30 years and spent 18 years in and out of prison. He attended the harm reduction program at Penitentiary no. 4-Cricova in Moldova. He volunteered for the prison’s needle and syringe program, providing sterile needles to other inmates to help protect others from HIV. “I became someone the other guys in prison could trust,” he says. “I would listen to them and share my own story.”

Investing for Impact

The Global Fund provides 28% of all international financing for HIV programs and has invested a total of US$26.6 billion in programs to prevent and treat HIV and AIDS and US$5.5 billion in TB/HIV programs as of June 2024. Global Fund investments to tackle HIV not only drive progress against the disease, but also contribute to building strong, equitable and resilient health and community systems.

Today, we have the knowledge and tools to prevent every new HIV infection and each AIDS-related death. The gains made against HIV in 2023 build on more than two decades of acceleration and progress. The Global Fund partnership is now focused on finishing the fight against HIV and AIDS by 2030.

Progress Towards the Global Targets

Ending AIDS as a public health threat has never been more possible. Eswatini, for example, has achieved the 95-95-95 targets (95% of people living with HIV know their HIV status, 95% of people who know that they are living with HIV are on lifesaving antiretroviral therapy, and 95% of people who are on treatment are virally suppressed). Steadfast commitment from the government and the strong role of communities have been key in driving this progress.

But many countries are still off track to achieve the target of ending AIDS by 2030, particularly in relation to the number of new HIV infections still occurring. But by taking bold action now – which means supporting countries to ensure HIV services and programs are people-centered, promote human rights and gender equality, and are delivered in ways that maximize uptake, use and impact – we can reverse this trend and end AIDS by 2030.

Historical trend
Continuation of recent trend
Global target pathway to 2030
2030 target

AIDS-related deaths: Progress towards the UNAIDS target

New HIV infections: progress towards the UNAIDS target

“Continuation of recent trend” projection is based on the continuation of 2017-2022 trends. “Global target pathway to 2030” is based on the target from the 2023 UNAIDS Global AIDS Update. Countries that have recently received Global Fund HIV and AIDS funding and have reported programmatic results over the past two cycles. Global Fund Regional Groupings. Based on published data from UNAIDS (2024 release). 

Liz Tatiana Mereles and her 9-year-old son Tiago Masi enjoy a quiet moment together after their X-ray and TB test at CAMSAT in San Felipe, Asunción, Paraguay. Liz has four children. Flooding in Asunción has forced them from their home eight times over the past 13 years. CAMSAT provides people like Liz and her family with a safe, convenient, comfortable place to test for TB.

Tuberculosis: State of the Fight

Key TB results in 2023 in countries where the Global Fund invests:

Programmatic results achieved during 2023 by countries and regions where the Global Fund invests. Global Fund Regional Groupings.

In 2023, TB programs registered a complete recovery from the impact of COVID-19.

The significant recovery and acceleration in screening and testing we saw from 2022 has been sustained and efforts to find undiagnosed people have accelerated. Taken together with widening rollout of innovations and tools to enhance efficiency, strengthened commitments at the national and international level and progress in diagnostics, drugs and vaccine development – the outlook for TB is evolving in a hopeful and positive direction.

TB treatment coverage

TB treatment success rate

MDR-TB treatment success rate

HIV+ TB patients on ARVs

All data is based on estimates from Global Tuberculosis Report 2023. Global Fund disbursements are available on the Global Fund Data Explorer. Global Fund Regional Groupings.
Marketing professional Nguyen Ngoc Huyen at the National Lung Hospital in Hanoi, Viet Nam, where she received treatment for TB, lupus and COVID-19.

But TB continues to be fueled by inequity, and millions of people continue to live with and die from TB without ever receiving a diagnosis. The disease killed an estimated 1.3 million people in 2022.

In 2023, the Global Fund partnership continued to support countries to deliver equitable, people-centered, cost-effective TB interventions; prioritized finding and treating “missing” people with TB and drug-resistant TB; supported the rollout of better treatment regimens; increased the availability of people-centered, accessible, and quality screening and diagnostics; and addressed the structural drivers of TB and barriers to TB services, including gender and human rights challenges.

Trends in TB Burden

In countries where the Global Fund invests, TB deaths (excluding people living with HIV) have been reduced by 36% between 2002 and 2022, while new TB cases (all forms) have dropped by 1%. In the absence of TB control measures, deaths would have increased by 129% and TB cases by 38% in the same period.

With TB control (actual)
If there had been no TB control

Trends in TB deaths (excluding HIV-positive)

Trends in new TB cases (all forms)

TB burden estimates from WHO Global TB Report 2023. Estimation of “no TB control” trends for TB deaths from WHO and for new TB cases based on the assumption of constant trend in new TB cases since 2000. While major control efforts for malaria and HIV began with the launch of the Millennium Development Goals in 2000, TB control efforts began much earlier. The counter-factual and actual results therefore diverged from each other much earlier, making this graph look considerably different than its HIV and malaria counterparts. Global Fund portfolio indicates countries that have recently received Global Fund TB funding and have reported programmatic results over the past two cycles. Global Fund Regional Groupings.

Investing for Impact

The Global Fund provides 76% of all international financing for TB and has invested US$9.9 billion in programs to prevent and care for people with TB and US$1.9 billion in TB/HIV programs as of June 2024. Our investments in TB programs globally are reinforcing health and community systems, making them more resilient, sustainable and inclusive.

In Chak 168 GB Sirāj, near Faisalabad, Pakistan, a mobile van equipped with an X-ray machine and GeneXpert technology offers TB diagnostic services free of charge.

To end TB as a public health threat, we must remain laser-focused on bridging the gaps in prevention, treatment and care that persist.

Progress Towards the Global Targets

In 2023, TB programs in countries where the Global Fund invests achieved a complete recovery from COVID-19-related disruption. We found more people with TB than ever before – 7.1 million people were put on treatment.

Country efforts are at the center of this progress. India, which has the world’s largest TB burden, treated 2.4 million people1 for TB in 2023, up from 1.7 million just six years before. And as a result of strong domestic resource commitments to their TB program in recent years, Indonesia has been able to increase the number of people treated for TB from 339,000 in 2021 to 783,000 in 2023.

Despite that progress, we are still off track to end TB as a public health threat by 2030. To get there, we must do more. An all-in response to TB today actively contributes to building a safer, healthier and more equitable world tomorrow.

[1] https://www.who.int/teams/global-tuberculosis-programme/data#prov_notifications

Historical trend
Continuation of recent trend
Global target pathway to 2030
2030 target

TB deaths: progress towards the WHO target*

TB incidence rate: progress towards the WHO target 

*TB deaths include HIV-positive. “Continuation of recent trend” projection is based on reverting to pre-COVID-19 (2014-2019) trends. “Global target pathway to 2030” is based on targets from the WHO End TB Strategy. Countries that have recently received Global Fund TB funding and have reported programmatic results over the past two cycles. Global Fund Regional Groupings. Based on published data from Global Tuberculosis Report 2023. 

Obinna Amyaoha, a member of the logistics staff at the Gabasawa mosquito net hub in Kano State, Nigeria, inspects bales of mosquito nets destined for distribution throughout the state.

Malaria: State of the Fight

Key malaria results in 2023 in countries where the Global Fund invests:

Programmatic results achieved during 2023 by countries and regions where the Global Fund invests. Global Fund Regional Groupings.

Malaria remains a daunting global health challenge. Conflict, climate change and increasing resistance to insecticides are jeopardizing the significant gains that the Global Fund partnership has made against malaria over the last two decades. But with investments to strengthen health systems and accelerate the targeted deployment of innovative tools and trusted prevention, testing and treatment methods, the Global Fund partnership is fighting back.

Mosquito nets population coverage

Mosquito nets population use

Suspected malaria cases tested

All data is based on estimates from World Malaria Report 2023. Global Fund disbursements are available on the Global Fund Data Explorer. Global Fund Regional Groupings.
In the shade of a tree in the Palawan jungle, Rhialoly Romero, an Indigenous community health worker and microscopist, examines blood smear samples for signs of the malaria parasite. On this day, Rhialoly and her fellow health workers examined over 200 malaria smear tests; one person tested positive and received immediate treatment.

In 2023, Global Fund-supported malaria programs lent a special focus to reaching children under 5 and pregnant women, who are most vulnerable to severe malaria. In 2023, 44.6 million children received seasonal malaria chemoprevention and 15.5 million pregnant women received preventive treatment for malaria in countries where we invest. Posting a full recovery from COVID-19-related disruption, our partnership expanded access to powerful tools to prevent and treat malaria, including new dual-insecticide mosquito nets, seasonal malaria chemoprevention for children at high risk of malaria, intermittent preventive treatment of malaria for pregnant women, indoor residual spraying, and antimalarial medicines.

Trends in Malaria Burden

Since 2010, countries with the highest malaria burden have achieved significant declines in the overall number of deaths and have been able to drive down incidence rates. In countries where the Global Fund invests, malaria deaths have reduced by 28% between 2002 and 2022. In the absence of malaria control measures, deaths would have increased by 90% and malaria cases by 79% in the same period. The malaria incidence rate has declined by 29% since 2002.

With malaria control (actual)
If there had been no malaria control

Trends in malaria deaths

Trends in malaria cases

Malaria burden estimates and estimation of “no malaria control” from WHO Global Malaria Programme, 2023 release. Global Fund portfolio indicates countries where the Global Fund invests. Global Fund Regional Groupings.

Investing for Impact

The Global Fund provides 62% of all international financing for malaria programs and has invested more than US$19.1 billion in malaria programs as of June 2024. The Global Fund’s investments in the fight against malaria are making far-reaching contributions to strengthening health and community systems, making them more resilient, sustainable and inclusive.

Members of a residual spraying team working for Tchau-Tchau Malaria gather before starting work at the Boane Health Centre in Mozambique.

As proved by Cabo Verde – certified malaria-free by WHO in 2024 – the target of ending malaria is within reach. But we must work even harder to regain lost progress and ensure that crises such as conflict and climate change do not derail our efforts.

In 2023, the Global Fund partnership continued to deliver on our promise: to save lives from HIV, TB and malaria, and work with countries to build stronger and more inclusive systems for health.
Peter Sands, Executive Director of the Global Fund
Progress Towards the Global Targets

Malaria remains a daunting global health challenge, and we are off track to meet the target of ending the disease as a public health threat by 2030. It is imperative to get back on track to fight malaria, to protect our gains and end this disease once and for all. With investments to accelerate the deployment of innovative tools, scale up interventions and strengthen critical health system capabilities, like disease surveillance, community health workers and last-mile logistics, we are fighting back.

Historical trend
Continuation of recent trend
Global target pathway to 2030
2030 target

Malaria mortality rate: progress towards the WHO target

Malaria incidence rate: progress towards the WHO target

“Continuation of recent trend” projection is based on reverting to pre-COVID-19 (2014-2019) trends. “Global target pathway to 2030” is based on targets from the WHO Global Technical Strategy for Malaria (2021 update). Countries that have recently received Global Fund malaria funding and have reported programmatic results over the past two cycles. Global Fund Regional Groupings. Based on published data from World Malaria Report 2023. 
Community health worker Lazare Kafando uses the mobile application Mhealth_Burkina to record and track patient data in Pousghin, Burkina Faso.
Warehouse officer Resty Nakate operates a very narrow aisle truck at the New Kajjansi Warehouse near Kampala, Uganda. With support from the Global Fund, this government-run facility holds and distributes essential health commodities to more than 3,500 health centers across the country.

Strengthening Health and Community Systems

We are investing more than ever before in building stronger health and community systems to support interventions to combat the three diseases, accelerate the path towards universal health coverage and reinforce preparedness against future threats, including pandemics, antimicrobial resistance and climate change. Our investments are supporting primary health care facilities, laboratories, supply chains, oxygen provision and community health workers. In 2023 alone, we invested US$1.8 billion2 in health and community systems.

As the largest multilateral grants provider for health systems strengthening, we are supporting countries to build more effective and resilient health delivery systems, including community systems that reach the poorest and most marginalized. We invest in strengthening health product value chains and securing increased supply capacity and lower health product prices through market shaping. In 2023, we invested US$142.4 million in expanding and strengthening laboratory and diagnostics capacities; US$98.6 million in surveillance systems to strengthen early detection and reporting capabilities for all hazards; and from 2021 to 2025, we are investing around US$564 million to expand access to lifesaving medical oxygen. The Global Fund has invested more than US$1.5 billion in community health workers since 2020 and is investing US$900 million more over the next three years.

Sirajul Islam with his 6-year-old daughter, Sumaiya, where their family home once stood in the village of Sreeula in Bangladesh. Every year, hundreds of thousands of people in Bangladesh leave their homes because of climate-related disasters and settle in cities, where inadequate hygiene and crowded conditions can fuel the spread of tuberculosis.

Colliding Crises

In the face of crises and challenging circumstances, we have repeatedly demonstrated our value in supporting countries to adapt to shocks to ensure sustainable progress against the three diseases and improve overall health outcomes.

In 2023, climate change, conflict, and attacks on human rights, gender equality and civil society caused enormous human suffering and deepened inequities within and between countries. While the impact and dynamics of these crises differ by region and country, the challenges invariably put the poorest and the most marginalized people at greater risk of deadly infectious diseases.

Since 2002, the Global Fund has provided more than US$22 billion to support crucial HIV, TB, and malaria prevention and treatment services and strengthen health and community systems in countries or regions that experience infectious disease outbreaks, natural disasters and hazards, armed conflicts or civil unrest, weak governance, climate change-related crises, and/or mass displacement.

To end HIV, TB and malaria as public health threats and address emerging dangers to global health security, we need to reach the most vulnerable people with prevention and treatment services, wherever they are.

Four-year-old Adil Shaikh Hassan in the Badawa neighborhood of Erbil, Iraq. Adil’s father and grandfather tested positive for TB; soon after, Adil tested positive as well. Adil receives a new pediatric formulation for TB – a drinkable, cherry-flavored medicine designed for children.

Investing for Impact

The Global Fund galvanizes the world to invest in the fight against the deadliest infectious diseases while challenging the injustice that continues to fuel them. Since our founding in 2002, the Global Fund has disbursed more than US$65.4 billion to support programs run by local experts in more than 100 countries. In 2023, we invested US$5 billion3 to fight deadly infectious diseases and strengthen health and community systems. This is the third year in a row of record investments for the Global Fund.

Our Results Methodology

The Global Fund Results Report 2024 presents selected programmatic results (e.g., people on antiretroviral therapy, people treated for TB, mosquito nets distributed) achieved by supported programs in 2023. The programmatic results are reported routinely to the Global Fund by the supported programs. The data collected by our technical partners are also used for cross-checking and triangulation and for furnishing national data for selected services to align with the Global Fund partnership’s approach in results reporting. The Global Fund also uses official disease burden and impact estimates developed and published by our technical partners, including the World Health Organization and UNAIDS, as the basis for measuring impact.

Learn more

[2] This includes direct investments in resilient and sustainable systems for health (RSSH) and contributions to RSSH through investments in the fight against HIV, TB and malaria.
[3] When including Strategic Initiative disbursements, this figure would amount to US$5.1 billion.

Full report
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At a Glance
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Annex
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Key Results and Lives Saved
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HIV: State of the Fight
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Tuberculosis: State of the Fight
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Malaria: State of the Fight
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Health and Community Systems
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Colliding Crises
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Investing for Impact
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