Children’s Investment Fund Foundation

Breaking the Cycle of HIV Transmission

Current pledge (2023-2025)
US$33.19 million
Partner since

In October 2022, the Children’s Investment Fund Foundation (CIFF), the world's largest philanthropic foundation focused on improving children's lives, pledged US$33 million for the Global Fund’s Seventh Replenishment for the period January 2023 to March 2028.

The pledge supports accelerating access to pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) for populations that need it most in Kenya, Mozambique, Nigeria, South Africa, Uganda and Zambia.

“While testing and treatment are essential tools in the fight against HIV, the ultimate goal is preventing transmission in the first place,” said Peter Sands, Executive Director of the Global Fund. “Through targeted deployment of PrEP, we can dramatically cut the number of new HIV infections. We are extremely grateful to CIFF for their new commitment, and we are proud to continue working alongside them.”

To end AIDS by 2030, 10 million PrEP initiations are needed. PrEP is a medicine that people at increased likelihood of acquiring HIV can take to prevent HIV infection. When used effectively, PrEP reduces the likelihood of getting HIV from sex by about 99%.

The Global Fund and CIFF have partnered to fight HIV since 2015 when CIFF pledged US$10 million to support pediatric HIV treatment and expand access to treatment in Zimbabwe and Kenya.

In 2019, CIFF and the Global Fund launched a US$25 million catalytic investment to scale up access to HIV self-tests in Cameroon, Mozambique, Nigeria, the United Republic of Tanzania and Uganda. This mechanism is fueling remarkable progress in sub-Saharan Africa, where the majority of those living with undiagnosed HIV reside. In five of Africa’s poorest countries, the distribution of self-tests has grown from a few thousand units in 2019 to over 4.6 million by June 2023. This partnership combines CIFF’s experience in innovative approaches and the Global Fund’s experience in offering broad HIV program support, taking innovation and new products to scale, and supporting country leadership in the HIV response.

“The Global Fund has a track record of deploying well-governed public-private partnerships within its country-led approach to scale proven innovations,” said Chris Hohn, Founder of CIFF. “Equal access to lifesaving products like PrEP is, tragically, not a given across the world. Catalytic investments at the right time, with organizations like the Global Fund, can change this, increasing the impact of philanthropic funds and saving millions of lives.”