Response Mechanism

The COVID-19 Response Mechanism (C19RM) has awarded US$4.3 billion to 131 countries since April 2020, to mitigate the impact of the COVID-19 pandemic on programs to fight HIV, tuberculosis (TB) and malaria and initiate urgent improvements in formal and community health systems. Funding awarded through C19RM is available until 31 December 2023. Implementing countries are encouraged to look at opportunities for refocusing C19RM funding in line with evolving epidemiological country contexts.

Read the latest updates on C19RM

C19RM funds the following areas: COVID-19 Response; COVID-19 related adaptation of programs to fight HIV, TB and malaria; and strengthening formal and community health systems. These three areas should also incorporate cross-cutting activities that bolster community responses to COVID-19 and support pandemic preparedness.

Activities to be funded are aligned with the relevant pillars of the COVID-19 Strategic Preparedness and Response Plan (SPRP). More information can be found in the technical guidance documents.


The COVID-19 pandemic is evolving and so should C19RM investments. The Global Fund would like to support implementing countries to rethink how these funds need to be adapted to their needs in a dynamic pandemic context. The COVID-19 pandemic is not yet over and investments in this area are still needed. C19RM funds provide an opportunity to invest in building up the capabilities of health systems across a range of potential epidemic scenarios, strengthening resilience and preparing for the next pandemic.

Principal Recipients of C19RM funding are asked to adapt C19RM funding and interventions to evolving country circumstances. As the pandemic evolves, reinvesting potentially unutilized funds optimizes the impact of C19RM investments.

Learn more about opportunities for reinvestment of C19RM funding